Datasets_Visualizations

Neuroblastoma

Yunyun Xu*, Daohua Lou*, Ping Chen*, Gang Li*, Dimtry Usoskin, Jian Pan, Fang Li, Shungen Huang, Caroline Hess, Ruze Tang, Xiaohan Hu, Juanjuan Yu, Maria Arceo, Ronald R. de Krijger, Arthur S. Tischler, Susanne Schlisio, Patrik Ernfors#, Yizhou Hu#, Jian Wang# “Single-cell MultiOmics and spatial transcriptomics demonstrate neuroblastoma developmental plasticity”, Developmental Cell, 2025. doi: https://doi.org/10.1016/j.devcel.2025.04.013

Genome Sequence Archive: HRA004944, HRA004933 in https://ngdc.cncb.ac.cn/gsa-human/

Shinyapps website of integrated neuroblastoma scRNAseq data: https://yz-studio.shinyapps.io/dev_nbl/

Shinyapps website of neuroblastoma spatial transcriptomics data: https://yz-studio.shinyapps.io/NBL_ST/

Shinyapps website of single-cell MultiOmics (RNA+ATAC) data of mouse (Dbh-cre; MYCN, N2A) neuroblastoma cells: https://yz-studio.shinyapps.io/scMultiOmics_mouseNBLcells/

Hu Y.#, Jiang Y.#, Behnan J., Ribeiro MM., Kalantzi C., Zhang M., Lou D., Haring M., Sharma N., Okawa S., Del Sol A., Adameyko I., Svensson M., Persson O., Ernfors P., “Neural-network learning defines glioblastoma features to be of neural crest perivascular or radial glia lineages”, Science Advances, 2022 Jun 10;8(23). https://www.science.org/doi/10.1126/sciadv.abm6340

Gene Expression Omnibus: GSE159416 and GSE171287 in https://www.ncbi.nlm.nih.gov/geo

“Single cell transcriptional zonation of human psoriasis skin identifies an alternative immunoregulatory axis”, Cell Death Dis., 2021 May 6;12(5):450. Link: https://pubmed.ncbi.nlm.nih.gov/33958582/

“Integrative single-cell transcriptomic investigation unveils long non-coding RNAs associated with localized cellular inflammation in psoriasis”, Front Immunol. 2023 Sep 26;14:1265517. Link: https://pubmed.ncbi.nlm.nih.gov/37822943/

Integrated dataset: 106,675 cells from 11 healthy human skin and 79,887 cells from 9 psoriatic human skin.